ENTRY EC 1.14.16.5
NAME Glyceryl-ether monooxygenase
Glyceryl-ether cleaving enzyme
CLASS Oxidoreductases
Acting on paired donors with incorporation of molecular oxygen
With reduced pteridine as one donor, and incorporation of
one atom of oxygen
SYSNAME 1-Alkyl-sn-glycerol,tetrahydrobiopterin:oxygen oxidoreductase
REACTION 1-Alkyl-sn-glycerol + Tetrahydrobiopterin + O2 =
1-Hydroxyalkyl-sn-glycerol + Dihydrobiopterin + H2O
SUBSTRATE 1-Alkyl-sn-glycerol
Tetrahydrobiopterin
O2
PRODUCT 1-Hydroxyalkyl-sn-glycerol
Dihydrobiopterin
H2O
COFACTOR Glutathione
Phospholipid
COMMENT Requires reduced glutathione and phospholipids for full activity.
The product spontaneously breaks down to form a fatty aldehyde
and glycerol. Formerly EC 1.14.99.17.
DBLINKS University of Geneva ENZYME DATA BANK: 1.14.16.5
WIT (What Is There) Metabolic Reconstruction: 1.14.16.5
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