ENTRY EC 1.14.15.3
NAME Alkane 1-monooxygenase
Alkane 1-hydroxylase
omega-Hydroxylase
Fatty acid omega-hydroxylase
CLASS Oxidoreductases
Acting on paired donors with incorporation of molecular oxygen
With a reduced iron-sulfur protein as one donor, and
incorporation of one atom of oxygen
SYSNAME Alkane,reduced-rubredoxin:oxygen 1-oxidoreductase
REACTION Octane + Reduced rubredoxin + O2 = 1-Octanol +
Oxidized rubredoxin + H2O
SUBSTRATE Octane
Reduced rubredoxin
O2
Fatty acid
PRODUCT 1-Octanol
Oxidized rubredoxin
H2O
omega-Hydroxy fatty acid
COFACTOR Heme
COMMENT Some enzymes in this group are heme-thiolate proteins (P-450).
Also hydroxylates fatty acids in the omega-position.
PATHWAY PATH: MAP00071 Fatty acid metabolism
MOTIF PS: PS00086 F-[SGNH]-x-[GD]-x-[RHPT]-x-C-[LIVMFAP]-[GAD]
DBLINKS University of Geneva ENZYME DATA BANK: 1.14.15.3
WIT (What Is There) Metabolic Reconstruction: 1.14.15.3
///
DBGET integrated database retrieval system,
GenomeNet