ENTRY       EC 1.14.13.9
NAME        Kynurenine 3-monooxygenase
            Kynurenine 3-hydroxylase
CLASS       Oxidoreductases
            Acting on paired donors with incorporation of molecular oxygen
            With NADH or NADPH as one donor, and incorporation of one atom of
            oxygen
SYSNAME     L-Kynurenine,NADPH:oxygen oxidoreductase (3-hydroxylating)
REACTION    L-Kynurenine + NADPH + O2 = 3-Hydroxy-L-kynurenine + NADP+ + H2O
SUBSTRATE   L-Kynurenine
            NADPH
            O2
PRODUCT     3-Hydroxy-L-kynurenine
            NADP+
            H2O
COFACTOR    FAD
COMMENT     A flavoprotein (FAD).  Formerly EC 1.14.1.2 and 1.99.1.5.
PATHWAY     PATH: MAP00380  Tryptophan metabolism
DBLINKS     University of Geneva ENZYME DATA BANK: 1.14.13.9
            WIT (What Is There) Metabolic Reconstruction: 1.14.13.9
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