ENTRY       EC 1.14.13.7
NAME        Phenol 2-monooxygenase
            Phenol hydroxylase
CLASS       Oxidoreductases
            Acting on paired donors with incorporation of molecular oxygen
            With NADH or NADPH as one donor, and incorporation of one atom of
            oxygen
SYSNAME     Phenol,NADPH:oxogen oxidoreductase (2-hydroxylating)
REACTION    Phenol + NADPH + O2 = Catechol + NADP+ + H2O
SUBSTRATE   Phenol
            NADPH
            O2
            Resorcinol
            o-Cresol
PRODUCT     Catechol
            NADP+
            H2O
            Pyrogallol
            2,3-Dihydroxytoluene
COFACTOR    FAD
COMMENT     A flavoprotein (FAD). Also active with resorcinol and o-cresol.
PATHWAY     PATH: MAP00360  Phenylalanine metabolism
MOTIF       PS: PS00197  C-{C}-{C}-[GA]-{C}-C-[GAST]-{cpdhtmEKRHFYW}-C
STRUCTURES  PDB: 1HQI  
DBLINKS     University of Geneva ENZYME DATA BANK: 1.14.13.7
            WIT (What Is There) Metabolic Reconstruction: 1.14.13.7
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