ENTRY       EC 1.14.13.59
NAME        L-Lysine 6-monooxygenase (NADPH)
CLASS       Oxidoreductases
            Acting on paired donors with incorporation of molecular oxygen
            With NADH or NADPH as one donor, and incorporation of one atom of
            oxygen
REACTION    L-Lysine + NADPH + O2 = N6-Hydroxy-L-lysine + NADP+ + H2O
SUBSTRATE   L-Lysine
            NADPH
            O2
PRODUCT     N6-Hydroxy-L-lysine
            NADP+
            H2O
COMMENT     The enzyme from a strain of E.coli is highly specific for L-Lysine;
            L-Ornithine and L-Homolysine are, for example, not substrates.
            EC 1.13.12.10 catalyses the same reaction, but without the
            involvenent of NADP.
DBLINKS     University of Geneva ENZYME DATA BANK: 1.14.13.59
            WIT (What Is There) Metabolic Reconstruction: 1.14.13.59
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