ENTRY       EC 1.14.13.43
NAME        Questin monooxygenase
CLASS       Oxidoreductases
            Acting on paired donors with incorporation of molecular oxygen
            With NADH or NADPH as one donor, and incorporation of one atom of
            oxygen
SYSNAME     Questin,NADPH:oxygen oxidoreductase (hydroxylating,
            $ anthraquinone-ring-opening)
REACTION    Questin + NADPH + O2 = Sulochrin + NADP+ + H2O
SUBSTRATE   Questin
            NADPH
            O2
PRODUCT     Sulochrin
            NADP+
            H2O
COMMENT     The enzyme cleaves the anthraquinone ring of questin to form a
            benzophenone.  Involved in the biosynthesis of the
            seco-anthraquinone (+)-geodin.
DBLINKS     University of Geneva ENZYME DATA BANK: 1.14.13.43
            WIT (What Is There) Metabolic Reconstruction: 1.14.13.43
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