ENTRY       EC 1.14.13.41
NAME        Tyrosine N-monooxygenase
            Tyrosine N-hydroxylase
CLASS       Oxidoreductases
            Acting on paired donors with incorporation of molecular oxygen
            With NADH or NADPH as one donor, and incorporation of one atom of
            oxygen
SYSNAME     L-Tyrosine,NADPH:oxygen oxidoreductase (N-hydroxylating)
REACTION    L-Tyrosine + NADPH + O2 = N-Hydroxy-L-tyrosine + NADP+ + H2O
SUBSTRATE   L-Tyrosine
            NADPH
            O2
PRODUCT     N-Hydroxy-L-tyrosine
            NADP+
            H2O
COFACTOR    Heme
COMMENT     A heme-thiolate protein (P-450).
PATHWAY     PATH: MAP00350  Tyrosine metabolism
            PATH: MAP00460  Cyanoamino acid metabolism
DBLINKS     University of Geneva ENZYME DATA BANK: 1.14.13.41
            WIT (What Is There) Metabolic Reconstruction: 1.14.13.41
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