ENTRY       EC 1.14.13.38
NAME        Anhydrotetracycline monooxygenase
            ATC oxygenase
CLASS       Oxidoreductases
            Acting on paired donors with incorporation of molecular oxygen
            With NADH or NADPH as one donor, and incorporation of one atom of
            oxygen
SYSNAME     Anhydrotetracycline,NADPH:oxygen oxidoreductase (6-hydroxylating)
REACTION    Anhydrotetracycline + NADPH + O2 = 12-Dehydrotetracycline +
            NADP+ + H2O
SUBSTRATE   Anhydrotetracycline
            NADPH
            O2
PRODUCT     12-Dehydrotetracycline
            NADP+
            H2O
COMMENT     Involved in the biosynthesis of the antibiotics tetracyclines in
            Streptomyces sp.
DBLINKS     University of Geneva ENZYME DATA BANK: 1.14.13.38
            WIT (What Is There) Metabolic Reconstruction: 1.14.13.38
///