ENTRY EC 1.14.13.37
NAME Methyltetrahydroprotoberberine 14-monooxygenase
Methyltetrahydroprotoberberine 14-hydroxylase
CLASS Oxidoreductases
Acting on paired donors with incorporation of molecular oxygen
With NADH or NADPH as one donor, and incorporation of one atom of
oxygen
SYSNAME (S)-N-Methylcanadine,NADPH:oxygen oxidoreductase
$ (14-hydroxylating)
REACTION (S)-N-Methylcanadine + NADPH + O2 = Allocryptopine + NADP+ + H2O
SUBSTRATE (S)-N-Methylcanadine
NADPH
O2
PRODUCT Allocryptopine
NADP+
H2O
COFACTOR Heme
COMMENT A heme-thiolate protein (P-450).
DBLINKS University of Geneva ENZYME DATA BANK: 1.14.13.37
WIT (What Is There) Metabolic Reconstruction: 1.14.13.37
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