ENTRY       EC 1.14.13.33
NAME        4-Hydroxybenzoate 3-monooxygenase (NAD(P)H)
CLASS       Oxidoreductases
            Acting on paired donors with incorporation of molecular oxygen
            With NADH or NADPH as one donor, and incorporation of one atom of
            oxygen
SYSNAME     4-Hydroxybenzoate,NAD(P)H:oxygen oxidoreductase (3-hydroxylating)
REACTION    4-Hydroxybenzoate + NADH or NADPH + O2 = 3,4-Dihydroxybenzoate +
            NAD+ or NADP+ + H2O
SUBSTRATE   4-Hydroxybenzoate
            NADH
            NADPH
            O2
PRODUCT     3,4-Dihydroxybenzoate
            NAD+
            NADP+
            H2O
COFACTOR    FAD
COMMENT     A flavoprotein (FAD). The enzyme from Corynebacterium
            cyclohexanicum is highly specific for 4-hydroxybenzoate, but uses
            NADH and NADPH at approximately equal rates (cf. EC 1.14.13.2).
PATHWAY     PATH: MAP00360  Phenylalanine metabolism
DBLINKS     University of Geneva ENZYME DATA BANK: 1.14.13.33
            WIT (What Is There) Metabolic Reconstruction: 1.14.13.33
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