ENTRY       EC 1.14.13.24
NAME        3-Hydroxybenzoate 6-monooxygenase
            3-Hydroxybenzoate 6-hydroxylase
CLASS       Oxidoreductases
            Acting on paired donors with incorporation of molecular oxygen
            With NADH or NADPH as one donor, and incorporation of one atom of
            oxygen
SYSNAME     3-Hydroxybenzoate,NADH:oxygen oxidoreductase (6-hydroxylating)
REACTION    3-Hydroxybenzoate + NADH + O2 = 2,5-Dihydroxybenzoate + NAD+ + H2O
SUBSTRATE   3-Hydroxybenzoate
            NADH
            O2
PRODUCT     2,5-Dihydroxybenzoate
            NAD+
            H2O
COFACTOR    FAD
COMMENT     A flavoprotein (FAD). Acts also on a number of analogues of
            3-hydroxybenzoate substituted in the 2, 4, 5 and 6 positions;
            NADPH can act instead of NADH, more slowly.
PATHWAY     PATH: MAP00360  Phenylalanine metabolism
DBLINKS     University of Geneva ENZYME DATA BANK: 1.14.13.24
            WIT (What Is There) Metabolic Reconstruction: 1.14.13.24
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