ENTRY       EC 1.14.13.22
NAME        Cyclohexanone monooxygenase
CLASS       Oxidoreductases
            Acting on paired donors with incorporation of molecular oxygen
            With NADH or NADPH as one donor, and incorporation of one atom of
            oxygen
SYSNAME     Cyclohexanone,NADPH:oxygen oxidoreductase (6-hydroxylating
            1,2-lactonizing)
REACTION    Cyclohexanone + NADPH + O2 = 6-Hexanolide + NADP+ + H2O
SUBSTRATE   Cyclohexanone
            Cyclic ketone
            NADPH
            O2
PRODUCT     6-Hexanolide
            NADP+
            H2O
COFACTOR    FAD
COMMENT     A flavoprotein (FAD). Acts on a number of other cyclic ketones.
PATHWAY     PATH: MAP00930  Metabolism of xenobiotics
DBLINKS     University of Geneva ENZYME DATA BANK: 1.14.13.22
            WIT (What Is There) Metabolic Reconstruction: 1.14.13.22
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