ENTRY       EC 1.14.13.20
NAME        2,4-Dichlorophenol 6-monooxygenase
            2,4-Dichlorophenol hydroxylase
CLASS       Oxidoreductases
            Acting on paired donors with incorporation of molecular oxygen
            With NADH or NADPH as one donor, and incorporation of one atom of
            oxygen
SYSNAME     2,4-Dichlorophenol,NADPH:oxygen oxidoreductase(6-hydroxylating)
REACTION    2,4-Dichlorophenol + NADPH + O2 = 3,5-Dichlorocatechol + NADP+ +
            H2O
SUBSTRATE   2,4-Dichlorophenol
            NADPH
            O2
            4-Chlorophenol
            4-Chloro-2-methylphenol
            NADH
PRODUCT     3,5-Dichlorocatechol
            NADP+
            H2O
            4-Chlorocatechol
            5-Chloro-3-methylcatechol
            NAD+
COFACTOR    FAD
COMMENT     A flavoprotein (FAD). Also acts, more slowly, on 4-chlorophenol
            and 4-chloro-2-methylphenol; NADH can act instead of NADPH, but
            more slowly.
DBLINKS     University of Geneva ENZYME DATA BANK: 1.14.13.20
            WIT (What Is There) Metabolic Reconstruction: 1.14.13.20
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