ENTRY       EC 1.14.13.2
NAME        4-Hydroxybenzoate 3-monooxygenase
            p-Hydroxybenzoate hydroxylase
CLASS       Oxidoreductases
            Acting on paired donors with incorporation of molecular oxygen
            With NADH or NADPH as one donor, and incorporation of one atom of
            oxygen
SYSNAME     4-Hydroxybenzoate,NADPH:oxygen oxidoreductase (3-hydroxylating)
REACTION    4-Hydroxybenzoate + NADPH + O2 = Protocatechuate + NADP+ + H2O
SUBSTRATE   4-Hydroxybenzoate
            NADPH
            O2
PRODUCT     Protocatechuate
            NADP+
            H2O
COFACTOR    FAD
COMMENT     A flavoprotein (FAD). The enzyme from Pseudomonas is highly
            specific for NADPH (cf. EC 1.14.13.33).
PATHWAY     PATH: MAP00360  Phenylalanine metabolism
STRUCTURES  PDB: 1PXC  1PBC  1PBB  1IUX  1PBE  1PXB  1PDH  1PHH  1IUS  1IUT  
                 1IUW  1IUV  2PHH  1IUU  1PBD  1PXA  1PBF  
DBLINKS     University of Geneva ENZYME DATA BANK: 1.14.13.2
            WIT (What Is There) Metabolic Reconstruction: 1.14.13.2
            SCOP (Structural Classificaion of Proteins): 1.14.13.2
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