ENTRY       EC 1.14.13.13
NAME        Calcidiol 1-monooxygenase
            25-Hydroxycholecalciferol 1-hydroxylase
            25-Hydroxycholecalciferol 1-monooxygenase
CLASS       Oxidoreductases
            Acting on paired donors with incorporation of molecular oxygen
            With NADH or NADPH as one donor, and incorporation of one atom of
            oxygen
SYSNAME     Calcidiol,NADPH:oxygen oxidoreductase (1-hydroxylating)
REACTION    Calcidiol + NADPH + O2 = Calcitriol + NADP+ + H2O
SUBSTRATE   Calcidiol
            NADPH
            O2
PRODUCT     Calcitriol
            NADP+
            H2O
PATHWAY     PATH: MAP00100  Sterol biosynthesis
DBLINKS     University of Geneva ENZYME DATA BANK: 1.14.13.13
            WIT (What Is There) Metabolic Reconstruction: 1.14.13.13
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