ENTRY       EC 1.14.13.12
NAME        Benzoate 4-monooxygenase
CLASS       Oxidoreductases
            Acting on paired donors with incorporation of molecular oxygen
            With NADH or NADPH as one donor, and incorporation of one atom of
            oxygen
SYSNAME     Benzoate,NADPH:oxygen oxidoreductase(4-hydroxylating)
REACTION    Benzoate + NADPH + O2 = 4-Hydroxybenzoate + NADP+ + H2O
SUBSTRATE   Benzoate
            NADPH
            O2
PRODUCT     4-Hydroxybenzoate
            NADP+
            H2O
COFACTOR    Iron
            Tetrahydrobiopterin
COMMENT     Requires Fe2+ and tetrahydrobiopterin.
PATHWAY     PATH: MAP00360  Phenylalanine metabolism
MOTIF       PS: PS00086  F-[SGNH]-x-[GD]-x-[RHPT]-x-C-[LIVMFAP]-[GAD]
DBLINKS     University of Geneva ENZYME DATA BANK: 1.14.13.12
            WIT (What Is There) Metabolic Reconstruction: 1.14.13.12
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