ENTRY       EC 1.14.12.9
NAME        4-Chlorophenylacetate 3,4-dioxygenase
CLASS       Oxidoreductases
            Acting on paired donors with incorporation of molecular oxygen
            With NADH or NADPH as one donor, and incorporation of two atoms
            of oxygen into one donor
SYSNAME     4-Chlorophenylacetate,NADH:oxygen oxidoreductase
            $ (3,4-hydroxylating, dechlorinating)
REACTION    4-Chlorophenyl acetate + NADH + O2 + H2O =
            3,4-Dihydroxyphenyl acetate + Chloride + NAD+
SUBSTRATE   4-Chlorophenyl acetate
            NADH
            O2
            H2O
            4-Bromophenyl acetate
PRODUCT     3,4-Dihydroxyphenyl acetate
            Chloride
            Bromide
            NAD+
COFACTOR    Iron
COMMENT     A system containing a reductase and an iron-sulfur oxygenase, and
            no independent ferredoxin. Requires Fe2+.  Also acts on
            4-bromophenyl acetate.
DBLINKS     University of Geneva ENZYME DATA BANK: 1.14.12.9
            WIT (What Is There) Metabolic Reconstruction: 1.14.12.9
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