ENTRY       EC 1.11.1.7
NAME        Peroxidase
CLASS       Oxidoreductases
            Acting on a peroxide as acceptor
SYSNAME     Donor:hydrogen-peroxide oxidoreductase
REACTION    Donor + H2O2 = Oxidized donor + 2 H2O
SUBSTRATE   Donor
            H2O2
PRODUCT     Oxidized donor
            H2O
COFACTOR    Heme
COMMENT     A hemeprotein.  In plants, this enzyme with laccase 
            (cf. EC 1.10.3.2) is a component of the lignin and lignan 
            biosynthesis enzyme system.
PATHWAY     PATH: MAP00360  Phenylalanine metabolism
            PATH: MAP00680  Methane metabolism
DISEASE     MIM: 254600  Myeloperoxidase; Myeloperoxidase deficiency (3)
MOTIF       PS: PS00435  [DET]-[LIVMTA]-x(2)-[LIVM]-[LIVMSTAG]-[SAG]-[LIVMSTAG]-
                         H-[STA]-[LIVMFY]
            PS: PS00436  [SGATV]-x(3)-[LIVMA]-R-[LIVMA]-x-[FW]-H-x-[SAC]
GENES       HSA: LPO MPO(Hs.1817) TPO(Hs.2041)
STRUCTURES  PDB: 1MNP  1MYP  1SCH  1ARP  1ARU  1ARV  1ARW  1ARX  1ARY  1GZA  
                 1GZB  1MHL  
DBLINKS     University of Geneva ENZYME DATA BANK: 1.11.1.7
            WIT (What Is There) Metabolic Reconstruction: 1.11.1.7
            SCOP (Structural Classificaion of Proteins): 1.11.1.7
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