ENTRY       EC 1.10.3.1
NAME        Catechol oxidase
            Diphenol oxidase
            o-Diphenolase
            Phenolase
            Polyphenol oxidase
            Tyrosinase
CLASS       Oxidoreductases
            Acting on diphenols and related substances as donors
            With oxygen as acceptor
SYSNAME     1,2-Benzenediol:oxygen oxidoreductase
REACTION    2 Catechol + O2 = 2 1,2-Benzoquinone + 2 H2O
SUBSTRATE   Catechol
            O2
            L-Tyrosine
            L-Dopa
PRODUCT     1,2-Benzoquinone
            H2O
            L-Dopa
            Dopaquinone
COFACTOR    Copper
COMMENT     A group of copper proteins, that act also on a variety of
            substituted catechols, and many of which also catalyse the
            reaction listed under EC 1.14.18.1; this is especially true for
            the classical tyrosinase.
PATHWAY     PATH: MAP00350  Tyrosine metabolism
MOTIF       PS: PS00497  H-x(4)-F-[LIVMFTP]-x-[FW]-H-R-x(2)-[LM]-x(3)-E
            PS: PS00498  D-P-x-F-[LIVMFYW]-x(2)-H-x(3)-D
DBLINKS     University of Geneva ENZYME DATA BANK: 1.10.3.1
            WIT (What Is There) Metabolic Reconstruction: 1.10.3.1
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