ENTRY       EC 1.1.3.35
NAME        Salutaridine synthase
            (R)-Reticuline oxidase (C-O phenol-coupling)
CLASS       Oxidoreductases
            Acting on the CH-OH group of donors
            With oxygen as acceptor
REACTION    (R)-Reticuline + NADPH + O2 = Salutaridine + NADP+ + 2 H2O
SUBSTRATE   (R)-Reticuline
            NADPH
            O2
PRODUCT     Salutaridine
            NADP+
            H2O
COMMENT     Forms the Merphinan alkaloid Salutaridine by intramolecular phenol
            oxidation of Reticuline without the incorpotation of oxygen into the
            product.
DBLINKS     University of Geneva ENZYME DATA BANK: 1.1.3.35
            WIT (What Is There) Metabolic Reconstruction: 1.1.3.35
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