ENTRY       EC 1.1.3.33
NAME        (S)-Cheilanthifoline synthase
            (S)-Scoulerine oxidase (methylenedioxy-bridge forming)
CLASS       Oxidoreductases
            Acting on the CH-OH group of donors
            With oxygen as acceptor
REACTION    (S)-Scoulerine + NADPH + O2 =
            (S)-Cheilanthifoline + NADP+ + 2 H2O
SUBSTRATE   (S)-Scoulerine
            NADPH
            O2
PRODUCT     (S)-Cheilanthifoline
            NADP+
            H2O
COMMENT     Catalyses an oxidative reaction that does not incorporate oxygen
            into the product. Forms the methylenedioxy bridge of the
            Protoberberine alkaloid Cheilanthifoline from oxidative ring closure
            of adjacent phenolic and methoxy groups of Scoulerine.
DBLINKS     University of Geneva ENZYME DATA BANK: 1.1.3.33
            WIT (What Is There) Metabolic Reconstruction: 1.1.3.33
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