ENTRY       EC 1.1.3.32
NAME        (S)-Stylopine synthase
            (S)-Cheilanthifoline oxidase (methylene-bridge forming)
CLASS       Oxidoreductases
            Acting on the CH-OH group of donors
            With oxygen as acceptor
REACTION    (S)-Cheilanthifoline + NADPH + O2 =
            (S)-Stylopine + NADP+ + 2 H2O
SUBSTRATE   (S)-Cheilanthifoline
            NADPH
            O2
PRODUCT     (S)-Stylopine
            NADP+
            H2O
COMMENT     Catalyses an oxidative reaction that does not incorporate oxygen
            into the product. Forms the second methylenedioxy bridge of the
            Protoberberine alkaloid Stylopine from oxidative ring closure of
            adjacent phenolic and methoxy groups of Cheilanthifoline.
DBLINKS     University of Geneva ENZYME DATA BANK: 1.1.3.32
            WIT (What Is There) Metabolic Reconstruction: 1.1.3.32
///