G-Protein Coupled Receptors

G-Protein Coupled Receptors

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Muscarinic acetylcholine receptors (see also: Nicotinic acetylcholine receptors)

Organism	ACHR
	Gs			Gi/Go
	M1	M3	M5	M2	M4
hsa [ P \| G \| T ]	CHRM1	CHRM3	CHRM5	CHRM2	CHRM4
mmu [ P \| G \| T ]					CHRM4
dme [ P \| G \| T ]	FBgn0000037
cel [ P \| G \| T ]	C15B12.5 F47D12.2

Adrenoreceptors

Organism	ADR
	Gq				Gi/Go			Gs
	alpha1A	alpha1B	alpha1C	alpha1D	alpha2A	alpha2B	alpha2C	beta1	beta2	beta3
hsa [ P \| G \| T ]	ADRA1A	ADRA1B	ADRA1C	ADRA1D	ADRA2A	ADRA2B	ADRA2C	ADRB1	ADRB2	ADRB3
mmu [ P \| G \| T ]	ADRA1A	ADRA1B			ADRA2A	ADRA2B	ADRA2C	ADRB1	ADRB2	ADRB3

Dopamine receptors

Organism	DR
	Gs		Gi/Go
	D1	D5	D2	D3	D4
hsa [ P \| G \| T ]	DRD1	DRD5	DRD2	DRD3	DRD4
mmu [ P \| G \| T ]	DRD1A	DRD5	DRD2	DRD3	DRD4
dme [ P \| G \| T ]			FBgn0015129

5-Hydroxytryptamine (serotonin) receptors (see also: 5HT3 receptor)

Organism	HTR
	Gi/Go					Gq			Gs
	5HT1A	5HT1B	5HT1D	5HT1E	5HT1F	5HT2A	5HT2B	5HT2C	5HT4	5HT5	5HT6	5HT7
hsa [ P \| G \| T ]	HTR1A	HTR1B	HTR1D	HTR1E	HTR1F	HTR2A	HTR2B	HTR2C	HTR4	HTR5A	HTR6	HTR7
mmu [ P \| G \| T ]	HTR1A	HTR1B		HTR1D HTR1DA HTR1DB	HTR1F	HTR2A		HTR2C		HTR5A HTR5B	HTR6	HTR7
dme [ P \| G \| T ]	FBgn0004168	FBgn0004572										FBgn0004573

Histamine receptors

Organism	HR
	Gq	Gs
	H1	H2
hsa [ P \| G \| T ]	HRH1	HRH2
mmu [ P \| G \| T ]	HRH1	HRH2

Adenosine receptors

Organism	ADOR
	Gi/Go	Gs		Gi
	A1	A2A	A2B	A3
hsa [ P \| G \| T ]	ADORA1	ADORA2A	ADORA2B	ADORA3
mmu [ P \| G \| T ]	(U05671)	(U05672)	(U05673)	ADORA3

Cannabinoid receptors

Organism	CNR
Organism	CB1	CB2
hsa [ P \| G \| T ]	CNR1	CNR2
mmu [ P \| G \| T ]	CNR1	CNR2

Melanocortin receptors

Organism	MCR
Organism	MC1	MC2	MC3	MC4	MC5
hsa [ P \| G \| T ]	MC1R	MC2R	MC3R	MC4R	MC5R
mmu [ P \| G \| T ]	MC1R	MC2R	MC3R		MC5R

P2Y receptors (see also: P2X receptors)

Organism	P2Y
	Gq
	P2Y1	P2Y2	P2Y4	P2Y6	P2Y11
hsa [ P \| G \| T ]	P2RY1	P2RY2	P2RY4	P2RY6	P2RY11

Angiotensin receptors

Organism	AGTR
	Gi	(Gi)
	AT1	AT2
hsa [ P \| G \| T ]	AGTR1 AGTR1B	AGTR2
mmu [ P \| G \| T ]	AGTR1A AGTR1B	AGTR2

Chemokine receptors

Organism	CKR
Organism	CCR1	CCR2	CCR3	CCR4	CCR5	CCR6	CCR7	CCR8	CXCR1	CXCR2	CXCR3	CXCR4	CXCR5	CX3CR1
hsa [ P \| G \| T ]	CCR1	CCR2	CCR3	CCR4	CCR5	CCR6	CCR7	CCR8	IL8RA	IL8RB	(P49682)	CXCR4	X68149	CX3CR1
mmu [ P \| G \| T ]	CMKBR1 CMKBR1L1 CMKBR1L2	CMKBR2		CMKBR4	CMKBR5			CMKAR2	CMKAR3	CMKAR4	X71788	CMKBR7

Opioid receptors

Organism	OPR
	Gi/Go
	mu	kappa	delta
hsa [ P \| G \| T ]	OPRM1	OPRK1	OPRD1
mmu [ P \| G \| T ]	OPRM	OPRK1

Prostanoid receptors

Organism	PGR
Organism	DP	EP1	EP2	EP3	EP4	FP	IP	TP
hsa [ P \| G \| T ]	PTGDR	PTGER1	PTGER2	PTGER3	PTGER4	PTGFR	PTGIR
mmu [ P \| G \| T ]	PTGDR	PTGER1	PTGER2		PTGER4	PTGFR	PTGIR	TBXA2R

Somatostatin receptors

Organism	SSTR
Organism	SST1	SST2	SST3	SST4	SST5
hsa [ P \| G \| T ]	SSTR1	SSTR2	SSTR3	SSTR4	SSTR5
mmu [ P \| G \| T ]	SMSTR1	SMSTR2	SMSTR3	SMSTR4	SMSTR5

Vasoactive intestinal peptide (VIP) receptors
Pituitary adenylate cyclase activating polypeptide (PACAP) receptors

Organism	VP
Organism	PAC1	VPAC1	VPAC2
hsa [ P \| G \| T ]	ADCYAP1R1	VIPR1	VIPR2
mmu [ P \| G \| T ]	ADCYAP1R1		VIPR2

Corticotropin-releasing factor receptors

Organism	CRHR
Organism	CRF1	CRF2
hsa [ P \| G \| T ]	CRHR1	CRHR2
mmu [ P \| G \| T ]	CRHR	CRHR2

Bradkinin receptors

Organism	BDKR
Organism	B1	B2
hsa [ P \| G \| T ]	BDKRB1	BDKRB2
mmu [ P \| G \| T ]		BDKRB2

Cholecystokinin receptors

Organism	CCKR
Organism	CCK1	CCK2
hsa [ P \| G \| T ]	CCKAR	CCKBR
mmu [ P \| G \| T ]	CCKAR	CCKBR

Endothelin receptors

Organism	EDNR
	Gq
	ETA	ETB
hsa [ P \| G \| T ]	EDNRA	EDNRB
mmu [ P \| G \| T ]		EDNRB

Melatonin receptors

Organism	MTNR
Organism	MLT1	MLT2	MLT3
hsa [ P \| G \| T ]	MTNR1A	MTNR1B
mmu [ P \| G \| T ]	MTNR1A

Metabotropic glutamate receptors (see also: Ionotropic glutamate receptors)

Organism	GRM
	Gq		Gi
	mGlu1	mGlu5	mGlu2	mGlu3	mGlu4	mGlu6	mGlu7	mGlu8
hsa [ P \| G \| T ]	GRM1	GRM5	GRM2	GRM3	GRM4	GRM6	GRM7	GRM8
dme [ P \| G \| T ]	FBgn0019985 FBgn0020430
cel [ P \| G \| T ]	F45H11.4

Last updated: August 6, 1999
Compiled by KEGG