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Genome Centres (G)

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This is a list of BioInformatics centres working on the Human (or other species) Genome.
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[info] Galton Laboratory
[info] GBF - Molecular Bioinformatics of Gene Regulation
[info] Généthon
[info] Genestream
[info] GenLink
[info] Genome Annotation Consortium
[info] GenomeNet, Japan
[info] Genopole
[info] Genoscope
[info] George M. Church Laboratory
[info] GIRI - Genetic Information Research Institute

Detailed information on the above options

Galton Laboratory

GBF - Molecular Bioinformatics of Gene Regulation
The GBF project"Molecular Bioinformatics of Gene Regulation" deals with the DNA sequence features of regulatory genomic elements and regions, in particular those that govern transcriptional control. The project comprises theroretical as well as experimental work. The basis of the theoretical part is the TRANSFAC database. It compiles data about gene regulatory DNA sequences and protein factors binding to them. On this basis, programs are developed that help to identify putative promoter or enhancer structures and to suggest their features. These efforts are part of ring funding projects GENUS (GEne regulatory NUcleic acid Sequences) financed by the BMBF (the previous BMFT) and TRADAT (TRAnscription DATabases and analysis tools) by the European Comission.


Genestream 2, at the Institut de Genetique Humaine, Montpellier

GenLink provides linkage mapping information and software tools that facilitate the integration of physical and genetic linkage data to produce unified maps of the human genome. Researchers interested in identifying genes based on map positions should find the resource helpful.

Genome Annotation Consortium
Our Mission: To address fundamental questions in the life sciences and provide information and analytical resources to the wider biology research community; and to achieve these goals by our research and development at the intersection of the life sciences, mathematics, information technology, and computational science.

GenomeNet, Japan
GenomeNet is a Japanese computer network for genome research and related research areas in molecular and cellular biology.

GENOPOLE in Evry, France, is a center of excellence dedicated to genome research and the advancement of biotechnology. Its mission is to contribute towards our deeper understanding of gene behavior and speed the transfer of that knowledge towards real-life applications in the fields of medicine, agriculture and the environment.

It includes:

In 1997, France decided to rejoin the group of countries which had initiated large scale sequencing, by deciding to create a"Groupement d'Interjt Public" : the Genoscope, for which the official notice of creation appeared in France's"Journal Officiel" on January 1st 1997.

The mission of Genoscope is to produce large quantities of sequencing data of excellent quality from genomes of diverse organisms (microbes, plants, animals and humans) of scientific, medical or economic interest. The main activities of the centre are divided into internal and external projects. The external projects are collaborations with laboratories in the public sector, or under contract, with those of the private sector.

George M. Church Laboratory

GIRI - Genetic Information Research Institute
Genetic Information Research Institute (GIRI) is a private, non-profit institution founded in 1994. Their mission is to understand biological processes which alter the the genetic makeup of different organisms, as a basis for potential gene therapy and genome engineering techniques.

They pursue and promote original peer-reviewed, public domain research on genetic information (DNA sequence data), as well as dissemination of databases and computer software related to this research.

Their research is heavily based on computer power and human skills different from those applied in classical molecular biology and genetics. As there are few established university departments devoted to this kind of research, the Institute is anticipating to play an active role in establishing computational biology as an independent field of research.

Any Comments, Questions? Support@hgmp.mrc.ac.uk