ENTRY       EC 6.3.4.8
NAME        Imidazoleacetate--phosphoribosyldiphosphate ligase
            5-Phosphoribosylimidazoleacetate synthetase
CLASS       Ligases
            Forming carbon-nitrogen bonds
            Other carbon--nitrogen ligases
SYSNAME     Imidazoleacetate:5-phosphoribosyl-diphosphate ligase (ADP- and
            $ pyrophosphate- forming)
REACTION    ATP + Imidazole-4-acetate + 5-Phosphoribosyl diphosphate = ADP +
            Orthophosphate + 1-(5-Phosphoribosyl)imidazole-4-acetate +
            Pyrophosphate
SUBSTRATE   ATP
            Imidazole-4-acetate
            5-Phosphoribosyl diphosphate
PRODUCT     ADP
            Orthophosphate
            1-(5-Phosphoribosyl)imidazole-4-acetate
            Pyrophosphate
PATHWAY     PATH: MAP00340  Histidine metabolism
DBLINKS     University of Geneva ENZYME DATA BANK: 6.3.4.8
            WIT (What Is There) Metabolic Reconstruction: 6.3.4.8
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