ENTRY       EC 6.3.3.3
NAME        Dethiobiotin synthase
CLASS       Ligases
            Forming carbon-nitrogen bonds
            Cyclo-ligases
SYSNAME     7,8-Diaminononanoate:carbon-dioxide cyclo-ligase
            (ADP-forming)
REACTION    ATP + 7,8-Diaminononanoate + CO2 = ADP + Orthophosphate +
            Dethiobiotin
SUBSTRATE   ATP
            7,8-Diaminononanoate
            CO2
            CTP
PRODUCT     ADP
            Orthophosphate
            Dethiobiotin
            CDP
COMMENT     CTP has half the activity of ATP.
PATHWAY     PATH: MAP00780  Biotin metabolism
GENES       MJA: MJ1299
            ECO: b0778(bioD)
            HIN: HI1445(bioD-A) HI1550(bioD-B)
            HPY: HP0029(bioD)
            BSU: bioD
            SYN: bioD) slr0523(ECOLI_745
            SCE: YNR057C(BIO4)
STRUCTURES  PDB: 1DAD  1DAE  1DAF  1DAG  1DAH  1DAI  1DBS  1DTS  
DBLINKS     University of Geneva ENZYME DATA BANK: 6.3.3.3
            WIT (What Is There) Metabolic Reconstruction: 6.3.3.3
            SCOP (Structural Classificaion of Proteins): 6.3.3.3
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