ENTRY       EC 6.2.1.13
NAME        Acetate--CoA ligase (ADP-forming)
            Acetyl-CoA synthetase (ADP-forming)
CLASS       Ligases
            Forming carbon-sulfur bonds
            Acid--thiol ligases
SYSNAME     Acetate:CoA ligase (ADP-forming)
REACTION    ATP + Acetate + CoA = ADP + Orthophosphate + Acetyl-CoA
SUBSTRATE   ATP
            Acetate
            CoA
            Propanoate
PRODUCT     ADP
            Orthophosphate
            Acetyl-CoA
            Propanoyl-CoA
COMMENT     Also acts on propanoate and, very slowly, on butanoate.
PATHWAY     PATH: MAP00620  Pyruvate metabolism
            PATH: MAP00640  Propanoate metabolism
DBLINKS     University of Geneva ENZYME DATA BANK: 6.2.1.13
            WIT (What Is There) Metabolic Reconstruction: 6.2.1.13
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