ENTRY EC 4.6.1.4
NAME Chorismate synthase
CLASS Lyases
Phosphorus-oxygen lyases
SYSNAME 5-O-(1-Carboxyvinyl)-3-phosphoshikimate phosphate-lyase
REACTION 5-O-(1-Carboxyvinyl)-3-phosphoshikimate = Chorismate +
Orthophosphate
SUBSTRATE 5-O-(1-Carboxyvinyl)-3-phosphoshikimate
PRODUCT Chorismate
Orthophosphate
COMMENT Shikimate is numbered so that the double-bond is between C-1 and
C-2, but some earlier papers numbered the ring in the reverse
direction.
PATHWAY PATH: MAP00400 Phenylalanine, tyrosine and tryptophan biosynthesis
MOTIF PS: PS00787 [DE]-[LIVM]-[NQ]-x(2)-L-x-R(2)-x(2)-G-x-[GS]-[KR]
PS: PS00788 R-[SA](3)-R-E-T
PS: PS00789 R-x-D-[PS]-[CA]-x(4)-A-x(2)-[LIVM]-x-E-A
GENES MJA: MJ1175(aroC)
MTH: MTH748
ECO: b2329(aroC)
HIN: HI0196(aroC)
HPY: HP0663(aroC)
BSU: aroF
SYN: sll1747(aroC)
SCE: YGL148W(ARO2)
DBLINKS University of Geneva ENZYME DATA BANK: 4.6.1.4
WIT (What Is There) Metabolic Reconstruction: 4.6.1.4
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