ENTRY       EC 4.3.1.3
NAME        Histidine ammonia-lyase
            Histidase
            Histidinase
            Histidine alpha-deaminase
CLASS       Lyases
            Carbon-nitrogen lyases
            Ammonia-lyases
SYSNAME     L-Histidine ammonia-lyase
REACTION    L-Histidine = Urocanate + NH3
SUBSTRATE   L-Histidine
PRODUCT     Urocanate
            NH3
PATHWAY     PATH: MAP00340  Histidine metabolism
            PATH: MAP00910  Nitrogen metabolism
DISEASE     MIM: 235800  Histidine ammonia-lyase (histidase); [Histidinemia]
                         (1)
MOTIF       PS: PS00488  G-[STG]-[LIVM]-[STG]-[AC]-S-G-[DH]-L-x-P-L-[SA]-x(2)-
                         [SA]
GENES       BSU: hutH
            HSA: HAL(HIS)
DBLINKS     University of Geneva ENZYME DATA BANK: 4.3.1.3
            WIT (What Is There) Metabolic Reconstruction: 4.3.1.3
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