ENTRY       EC 3.6.1.41
NAME        Bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
            Diadenosinetetraphosphatase (symmetrical)
            Dinucleosidetetraphosphate (symmetrical)
CLASS       Hydrolases
            Acting on acid anhydrides
            In phosphorus-containing anhydrides
SYSNAME     P1,P4-Dis(5'-nucleosyl)-tetraphosphate
            nucleotidebisphosphohydrolase
REACTION    P1,P4-Bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP
SUBSTRATE   P1,P4-Bis(5'-adenosyl) tetraphosphate
            H2O
            Bis(5'-guanosyl) tetraphosphate
            Bis(5'-adenosyl) pentaphosphate
PRODUCT     ADP
            GDP
COMMENT     Also acts on bis(5'-guanosyl) tetraphosphate and bis(5'-adenosyl)
            pentaphosphate, and, more slowly, on some other polyphosphates,
            forming a nucleoside bisphosphate as one product in all cases (cf.
            EC 3.6.1.17).
PATHWAY     PATH: MAP00230  Purine metabolism
GENES       ECO: b0049(apaH)
            HIN: HI0551(apaH)
            BSU: yjbP
DBLINKS     University of Geneva ENZYME DATA BANK: 3.6.1.41
            WIT (What Is There) Metabolic Reconstruction: 3.6.1.41
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