ENTRY EC 3.6.1.40
NAME Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase
Guanosine pentaphosphate phosphohydrolase
pppGpp 5'-phosphohydrolase
CLASS Hydrolases
Acting on acid anhydrides
In phosphorus-containing anhydrides
SYSNAME Guanosine-5'-triphosphate,3'-diphosphate 5'-phosphohydrolase
REACTION Guanosine 3'-diphosphate 5'-triphosphate + H2O =
Guanosine 3'-diphosphate 5'-diphosphate + Orthophosphate
SUBSTRATE Guanosine 3'-diphosphate 5'-triphosphate
H2O
PRODUCT Guanosine 3'-diphosphate 5'-diphosphate
Orthophosphate
COMMENT Also hydrolyses other guanosine 5'-triphosphate deivatives with
as least one unsubstituted phosphate group on the 3'-position, but
not GTP, ATP or adenosine 5'-triphosphate,3'-diphosphate.
PATHWAY PATH: MAP00230 Purine metabolism
GENES ECO: b3779(gppA)
HPY: HP0278(gppA)
DBLINKS University of Geneva ENZYME DATA BANK: 3.6.1.40
WIT (What Is There) Metabolic Reconstruction: 3.6.1.40
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