ENTRY       EC 3.5.4.23
NAME        Blasticidin-S deaminase
CLASS       Hydrolases
            Acting on carbon-nitrogen bonds, other than peptide bonds
            In cyclic amidines
SYSNAME     Blasticidin-S aminohydrolase
REACTION    Blasticidin S + H2O = Deaminohydroxyblasticidin S + NH3
SUBSTRATE   Blasticidin S
            H2O
            Cytomycin
            Acetylblasticidin S
PRODUCT     Deaminohydroxyblasticidin S
            NH3
COMMENT     Catalyses the deamination of the cytosine moiety of the
            antibiotics blasticidin S, cytomycin and acetylblasticidin S.
MOTIF       PS: PS00903  [CH]-[AV]-E-x(2)-[LIVMFGA]-[LIVM]-x(17,33)-P-C-x(2,8)-
                         C-x(3)-[LIVM]
DBLINKS     University of Geneva ENZYME DATA BANK: 3.5.4.23
            WIT (What Is There) Metabolic Reconstruction: 3.5.4.23
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