ENTRY EC 3.5.1.43
NAME Peptidyl-glutaminase
Peptidoglutaminase I
CLASS Hydrolases
Acting on carbon-nitrogen bonds, other than peptide bonds
In linear amides
SYSNAME Peptidyl-L-glutamine amidohydrolase
REACTION alpha-N-Peptidyl-L-glutamine + H2O = alpha-N-Peptidyl-L-glutamate
+ NH3
SUBSTRATE alpha-N-Peptidyl-L-glutamine
H2O
PRODUCT alpha-N-Peptidyl-L-glutamate
NH3
COMMENT Specific for the hydrolysis of the gamma-amide of glutamine
substituted at the alpha-amino group, e.g. glycyl-L-glutamine,
N-acetyl-L-glutamine and L-leucylglycyl-L-glutamine.
DBLINKS University of Geneva ENZYME DATA BANK: 3.5.1.43
WIT (What Is There) Metabolic Reconstruction: 3.5.1.43
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