ENTRY       EC 3.1.3.5
NAME        5'-Nucleotidase
CLASS       Hydrolases
            Acting on ester bonds
            Phosphoric monoester hydrolases
SYSNAME     5'-Ribonucleotide phosphohydrolase
REACTION    a 5'-Ribonucleotide + H2O = a Ribonucleoside + Orthophosphate
SUBSTRATE   5'-Ribonucleotide
            H2O
PRODUCT     Ribonucleoside
            Orthophosphate
COMMENT     Wide specificity for 5'-nucleotides.
PATHWAY     PATH: MAP00230  Purine metabolism
            PATH: MAP00240  Pyrimidine metabolism
            PATH: MAP00760  Nicotinate and nicotinamide metabolism
DISEASE     MIM: 129190  5' nucleotidase (CD73)
MOTIF       PS: PS00013  {DERK}(6)-[LIVMFWSTAG](2)-[LIVMFYSTAGCQ]-[AGS]-C
            PS: PS00785  [LIVM]-x-[LIVM](2)-[HEA]-[TI]-x-D-x-H-[GSA]
            PS: PS00786  [FY]-x(4)-[LIVM]-G-N-H-E-F-[DN]
GENES       MTH: MTH1492
            ECO: b0480(ushA)
            HIN: HI0206
            BSU: yfkN
            SYN: slr0306
            HSA: NT3 NT5(CD73) UMPH2
DBLINKS     University of Geneva ENZYME DATA BANK: 3.1.3.5
            WIT (What Is There) Metabolic Reconstruction: 3.1.3.5
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