ENTRY       EC 3.1.3.2
NAME        Acid phosphatase
            Acid phosphomonoesterase
            Phosphomonoesterase
            Glycerophosphatase
CLASS       Hydrolases
            Acting on ester bonds
            Phosphoric monoester hydrolases
SYSNAME     Orthophosphoric-monoester phosphohydrolase (acid optimum)
REACTION    an Orthophosphoric monoester + H2O = an Alcohol + Orthophosphate
SUBSTRATE   Orthophosphoric monoester
            H2O
PRODUCT     Alcohol
            Orthophosphate
INHIBITOR   (R,R)-Tartaric acid
COMMENT     Wide specificity. Also calyses transphosphorylations.
            Inhibited by L(+)-tartrate ( J.Biol.Chem 268, 20744-20746 (1993)).
PATHWAY     PATH: MAP00740  Riboflavin metabolism
            PATH: MAP00930  Metabolism of xenobiotics
DISEASE     MIM: 171640  Acid phosphatase 5, tartrate resistant
            MIM: 171650  Acid phosphatase 2, lysosomal; ?Lysosomal acid
                         phosphatase deficiency (1)
            MIM: 171790  Acid phosphatase, prostate
MOTIF       PS: PS00616  [LIVM]-x(2)-[LIVMA]-x(2)-[LIVM]-x-R-H-[GN]-x-R-x-[PA]
            PS: PS00778  [LIVMF]-x-[LIVMFA]-x(2)-[STAG]-H-D-[STANQ]-x-[LIVM]-
                         x(2)-[LIVMFY]-x(2)-[STA]
            PS: PS01157  G-S-Y-P-S-G-H-T
GENES       ECO: b0980(appA) b4055(aphA)
            SCE: YAR071W(PHO11) YBR092C(PHO3) YBR093C(PHO5) YDL024C(D2815)
                 YHR215W(PHO12) YPR073C(LTP1)
            HSA: ACP1(Hs.75393) ACP2(Hs.75589) ACP5(Hs.89806) ACPP(Hs.1852)
STRUCTURES  PDB: 3KBP  1RPT  1RPA  1PNT  1KBP  1BVH  4KBP  
DBLINKS     University of Geneva ENZYME DATA BANK: 3.1.3.2
            WIT (What Is There) Metabolic Reconstruction: 3.1.3.2
            SCOP (Structural Classificaion of Proteins): 3.1.3.2
///