ENTRY       EC 2.7.4.8
NAME        Guanylate kinase
            Deoxyguanylate kinase
CLASS       Transferases
            Transferring phosphorus-containing groups
            Phosphotransferases with a phosphate group as acceptor
SYSNAME     ATP:(d)GMP phosphotransferase
REACTION    ATP + GMP = ADP + GDP
SUBSTRATE   ATP
            GMP
            dGMP
            dATP
PRODUCT     ADP
            GDP
            dGDP
            dADP
COMMENT     dGMP can also act as acceptor, and dATP can act as donor.
PATHWAY     PATH: MAP00230  Purine metabolism
DISEASE     MIM: 139270  Guanylate kinase-1
MOTIF       PS: PS00856  T-T-R-x(2)-R-x(2)-E-x(2)-G-x(2)-Y-x-[FY]-[LIVMK]
GENES       ECO: b3648(gmk)
            HIN: HI1743(gmk)
            HPY: HP0321
            MGE: MG107(gmk)
            MPN: K04_orf239(gmk)
            SYN: slr1123(gmk)
            SCE: YDR454C(GUK1)
            HSA: GUK1 GUK2
STRUCTURES  PDB: 1GKY  
DBLINKS     University of Geneva ENZYME DATA BANK: 2.7.4.8
            WIT (What Is There) Metabolic Reconstruction: 2.7.4.8
            SCOP (Structural Classificaion of Proteins): 2.7.4.8
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