ENTRY EC 2.7.1.135
NAME Tau-protein kinase
CLASS Transferases
Transferring phosphorus-containing groups
Phosphotransferases with an alcohol group as acceptor
SYSNAME ATP:tau-protein O-phosphotransferase
REACTION ATP + tau-Protein = ADP + O-Phospho-tau-protein
SUBSTRATE ATP
tau-Protein
PRODUCT ADP
O-Phospho-tau-protein
EFFECTOR Tublin
COMMENT Activated by tublin. DIfferent from EC 2.7.1.123: not activated
by calmodulin, cyclic nucleotides or Ca2+. Involved in the
formation of paired helical filaments in brain. See comment on
EC 2.7.1.37.
DBLINKS University of Geneva ENZYME DATA BANK: 2.7.1.135
WIT (What Is There) Metabolic Reconstruction: 2.7.1.135
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