ENTRY       EC 2.7.1.119
NAME        Hygromycin-B kinase
CLASS       Transferases
            Transferring phosphorus-containing groups
            Phosphotransferases with an alcohol group as acceptor
SYSNAME     ATP:hygromycin-B 7''-O-phosphotransferase
REACTION    ATP + Hygromycin B = ADP + 7''-O-Phosphohygromycin
SUBSTRATE   ATP
            Hygromycin B
            1-N-Hydromicin
            Destomysin
PRODUCT     ADP
            7''-O-Phosphohygromycin
COMMENT     Phosphorylates the antibiotics hygromycin B, 1-N-hygromycin B
            and destomycin, but not hygromycin B2, at the 7''-hydroxyl group
            in the destomic acid ring.
DBLINKS     University of Geneva ENZYME DATA BANK: 2.7.1.119
            WIT (What Is There) Metabolic Reconstruction: 2.7.1.119
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