ENTRY       EC 2.5.1.16
NAME        Spermidine synthase
            Aminopropyltransferase
            Putrescine aminopropyltransferase
CLASS       Transferases
            Transferring alkyl or aryl groups, other than methyl groups
SYSNAME     S-Adenosylmethioninamine:putrescine 3-aminopropyltransferase
REACTION    S-Adenosylmethioninamine + Putrescine = 5'-Methylthioadenosine +
            Spermidine
SUBSTRATE   S-Adenosylmethioninamine
            Putrescine
PRODUCT     5'-Methylthioadenosine
            Spermidine
COMMENT     This enzyme is not identical with EC 2.5.1.22. The mammalian
            enzyme is highly specific but the bacterial enzyme can use other
            acceptors and can synthesize spermine.
PATHWAY     PATH: MAP00220  Urea cycle and metabolism of amino groups
            PATH: MAP00330  Arginine and proline metabolism
            PATH: MAP00410  beta-Alanine metabolism
DISEASE     MIM: 182891  Spermidine synthase-1
GENES       MJA: MJ0313
            ECO: b0121(speE)
            HPY: HP0832(speE)
            BSU: ywhF
            HSA: SRM(SRML1)
DBLINKS     University of Geneva ENZYME DATA BANK: 2.5.1.16
            WIT (What Is There) Metabolic Reconstruction: 2.5.1.16
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