ENTRY       EC 2.4.2.4
NAME        Thymidine phosphorylase
            Pyrimidine phosphorylase
CLASS       Transferases
            Glycosyltransferases
            Pentosyltransferases
SYSNAME     Thymidine:orthophosphate deoxyribosyltransferase
REACTION    Thymidine + Orthophosphate = Thymine +
            2-Deoxy-D-ribose 1-phosphate
SUBSTRATE   Thymidine
            Orthophosphate
PRODUCT     Thymine
            2-Deoxy-D-ribose 1-phosphate
COMMENT     The enzyme in some tissues also catalyses deoxyribosyltransferase
            reactions of the type catalysed by EC 2.4.2.6.
            (EC 2.4.2.6 Nucleoside deoxyribosyltramsferase)
PATHWAY     PATH: MAP00230  Purine metabolism
            PATH: MAP00240  Pyrimidine metabolism
DISEASE     MIM: 131222  Endothelial cell growth factor-1, platelet-derived
MOTIF       PS: PS00647  S-G-R-G-L-G-[HFY]-T-G-G-T-[LIVM]-D-K-L-E-[SA]-[IV]
GENES       MJA: MJ0667
            ECO: b4382(deoA)
            MGE: MG051(deoA)
            MPN: D09_orf421(deoA)
STRUCTURES  PDB: 1TPT  
DBLINKS     University of Geneva ENZYME DATA BANK: 2.4.2.4
            WIT (What Is There) Metabolic Reconstruction: 2.4.2.4
            SCOP (Structural Classificaion of Proteins): 2.4.2.4
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