ENTRY       EC 2.4.2.28
NAME        5'-methylthioadenosine phosphorylase
CLASS       Transferases
            Glycosyltransferases
            Pentosyltransferases
SYSNAME     5'-Methylthioadenosine:
            $orthophosphate methylthio-D-ribosyltransferase
REACTION    5'-Methylthioadenosine + Orthophosphate = Adenine +
            5-Methylthio-D-ribose 1-phosphate
SUBSTRATE   5'-Methylthioadenosine
            Orthophosphate
PRODUCT     Adenine
            5-Methylthio-D-ribose 1-phosphate
COMMENT     Also acts on 5'-deoxyadenosine and other analogues having 5'-deoxy
            groups.
DISEASE     MIM: 156540  Methylthioadenosine phosphorylase
GENES       MJA: MJ0060
            MTH: MTH1596
            HSA: MTAP(Hs.3245)
DBLINKS     University of Geneva ENZYME DATA BANK: 2.4.2.28
            WIT (What Is There) Metabolic Reconstruction: 2.4.2.28
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