ENTRY       EC 2.1.2.10
NAME        Aminomethyltransferase
            T-Protein
            Tetrahydrofolate aminomethyltransferase
CLASS       Transferases
            Transferring one-carbon groups
            Hydroxymethyl-, formyl- and related transferases
SYSNAME     S-Aminomethyldihydrolipoylprotein:(6S)-tetrahydrofolate
            aminomethyltransferase (ammonia-forming)
REACTION    (6S)-Tetrahydrofolate + S-Aminomethyldihydrolipoylprotein =
            (6R)-5,10-Methylenetetrahydrofolate + NH3 +
            Dihydrolipoylprotein
SUBSTRATE   (6S)-Tetrahydrofolate
            S-Aminomethyldihydrolipoylprotein
PRODUCT     (6R)-5,10-Methylenetetrahydrofolate
            NH3
            Dihydrolipoylprotein
COMMENT     A component, with EC 1.4.4.2 of the glycine cleavage system,
            formerly known as glycine synthase.
PATHWAY     PATH: MAP00260  Glycine, serine and threonine metabolism
            PATH: MAP00670  One carbon pool by folate
            PATH: MAP00910  Nitrogen metabolism
DISEASE     MIM: 238310  Aminomethyltransferase (glycine cleavage system
                         protein T); Hyperglycinemia, nonketotic, type II (1)
GENES       ECO: b2905(gcvT)
            BSU: yqhI(gcvT)
            SYN: sll0171(gcvT)
            SCE: YDR019C(GCV1)
            HSA: AMT(Hs.102)
DBLINKS     University of Geneva ENZYME DATA BANK: 2.1.2.10
            WIT (What Is There) Metabolic Reconstruction: 2.1.2.10
///