ENTRY EC 2.1.1.79
NAME Cyclopropane-fatty-acyl-phospholipid synthase
Cyclopropane synthetase
Unsaturated-phospholipid methyltransferase
CLASS Transferases
Transferring one-carbon groups
Methyltransferases
SYSNAME S-Adenosyl-L-methionine:unsaturated-phospholipid methyltransferase
$ (cyclizing)
REACTION S-Adenosyl-L-methionine + Phospholipid olefinic fatty acid =
S-Adenosyl-L-homocysteine +
Phospholipid cyclopropane fatty acid
SUBSTRATE S-Adenosyl-L-methionine
Phospholipid olefinic fatty acid
PRODUCT S-Adenosyl-L-homocysteine
Phospholipid cyclopropane fatty acid
COMMENT The enzyme adds a methylene group across the 9,10 position of a
delta9-olefinic acyl chain in phosphatidylethanolamine or, more
slowly, phosphatidylglycerol or phosphatidylinositol forming a
cyclopropane deirvative (cf. EC 2.1.1.16).
GENES ECO: b1661(CFA)
HPY: HP0416
DBLINKS University of Geneva ENZYME DATA BANK: 2.1.1.79
WIT (What Is There) Metabolic Reconstruction: 2.1.1.79
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