ENTRY       EC 2.1.1.75
NAME        Apigenin 4'-O-methyltransferase
            Flavonoid O-methyltransferase
CLASS       Transferases
            Transferring one-carbon groups
            Methyltransferases
SYSNAME     S-Adenosyl-L-methionine:5,7,4'-trihydroxyflavone
            $ 4'-O-methyltransferase
REACTION    S-Adenosyl-L-methionine + 5,7,4'-Trihydroxyflavone =
            S-Adenosyl-L-homocysteine + 4'-Methoxy-5,7-dihydroxyflavone
SUBSTRATE   S-Adenosyl-L-methionine
            5,7,4'-Trihydroxyflavone
            Naringenin
PRODUCT     S-Adenosyl-L-homocysteine
            Acacetin
            4'-Methoxy-5,7-dihydroxyflavonone
COMMENT     Converts apigenin into acacetin.  Naringenin (5,7,4'-trihydroxy-
            flavanone) can also act as acceptor, more slowly.
PATHWAY     PATH: MAP00940  Biosynthesis of flavonoids
DBLINKS     University of Geneva ENZYME DATA BANK: 2.1.1.75
            WIT (What Is There) Metabolic Reconstruction: 2.1.1.75
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