ENTRY       EC 2.1.1.72
NAME        Site-specific DNA-methyltransferase (adenine-specific)
            Modification methylase
            Restriction-Modification system
CLASS       Transferases
            Transferring one-carbon groups
            Methyltransferases
REACTION    S-Adenosyl-L-methionine + DNA adenine = S-Adenosyl-L-homocysteine
            + DNA 6-methylaminopurine
SUBSTRATE   S-Adenosyl-L-methionine
            DNA adenine
PRODUCT     S-Adenosyl-L-homocysteine
            DNA 6-methylaminopurine
COMMENT     This is a large group of enzymes most of which, with enzymes of
            similar site specificity listed as EC 3.1.21.3, 4 or 5, form so-
            -called 'restriction-modification systems'. A complelte listing of
            all the these enzymes has been produced by R.J.Roberts; this list
            is update annually.
MOTIF       PS: PS00092  [LIVAC]-[LIVFYWA]-x-[DN]-P-P-[FYW]
GENES       MJA: MJ0598 MJ1498
            ECO: b2330(yfcB) b3262(yhdJ) b3387(dam) b4349(hsdM)
            HIN: HI0209(dam) HI0513(hinDIIM) HI1392(hindIIIM)
            HPY: HP0050(dpnA) HP0054 HP0478 HP0481 HP0910 HP1352
            SYN: slr1378
STRUCTURES  PDB: 1AQI  1AQJ  2ADM  
DBLINKS     University of Geneva ENZYME DATA BANK: 2.1.1.72
            WIT (What Is There) Metabolic Reconstruction: 2.1.1.72
///

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