ENTRY EC 2.1.1.70
NAME 8-Hydroxyfuranocoumarin 8-O-methyltransferase
CLASS Transferases
Transferring one-carbon groups
Methyltransferases
SYSNAME S-Adenosyl-L-methionine:8-hydroxyfuranocoumarin
$ 8-O-methyltransferase
REACTION S-Adenosyl-L-methionine + 8-Hydroxyfuranocoumarin =
S-Adenosyl-L-homocysteine + 8-Methoxyfuranocoumarin
SUBSTRATE S-Adenosyl-L-methionine
8-Hydroxyfuranocoumarin
Xanthotoxol
PRODUCT S-Adenosyl-L-homocysteine
8-Methoxyfuranocoumarin
Xanthotoxin
COMMENT Converts xanthotoxol into xanthotoxin. Methylates the 8-hydroxyl
of some hydroxy- and methylcoumarins, but has little activity on
non-coumarin phenol.
DBLINKS University of Geneva ENZYME DATA BANK: 2.1.1.70
WIT (What Is There) Metabolic Reconstruction: 2.1.1.70
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