ENTRY EC 2.1.1.69
NAME 5-Hydroxyfuranocoumarin 5-O-methyltransferase
CLASS Transferases
Transferring one-carbon groups
Methyltransferases
SYSNAME S-Adenosyl-L-methionine:5-hydroxyfuranocoumarin
$ 5-O-methyltransferase
REACTION S-Adenosyl-L-methionine + 5-Hydroxyfuranocoumarin =
S-Adenosyl-L-homocysteine + 5-Methoxyfuranocoumarin
SUBSTRATE S-Adenosyl-L-methionine
5-Hydroxyfuranocoumarin
Bergaptol
PRODUCT S-Adenosyl-L-homocysteine
5-Methoxyfuranocoumarin
Bergapten
COMMENT Converts bergaptol into bergapten. Methylates the 5-hydroxyl of
some hydroxy- and methylcoumarins, but has little activity on
non-coumarin phenol.
DBLINKS University of Geneva ENZYME DATA BANK: 2.1.1.69
WIT (What Is There) Metabolic Reconstruction: 2.1.1.69
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