ENTRY       EC 2.1.1.38
NAME        O-Demethylpuromycin O-methyltransferase
CLASS       Transferases
            Transferring one-carbon groups
            Methyltransferases
SYSNAME     S-Adenosyl-L-methionine:O-demethylpuromycin O-methyltransferase
REACTION    S-Adenosyl-L-methionine + O-Demethylpuromycin =
            S-Adenosyl-L-homocysteine + Puromycin
SUBSTRATE   S-Adenosyl-L-methionine
            O-Demethylpuromycin
PRODUCT     S-Adenosyl-L-homocysteine
            Puromycin
COMMENT     Puromycin is the antibiotic derived from N6-dimethyladenosine
            by replacing the 3'-hydroxyl group with an amino group
            and acylating this with 4-O-methyltyrosine.
DBLINKS     University of Geneva ENZYME DATA BANK: 2.1.1.38
            WIT (What Is There) Metabolic Reconstruction: 2.1.1.38
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