ENTRY       EC 2.1.1.37
NAME        DNA (cytosine-5-)-methyltransferase
CLASS       Transferases
            Transferring one-carbon groups
            Methyltransferases
SYSNAME     S-Adenosyl-L-methionine:DNA (cytosine-5-)-methyltransferase
REACTION    S-Adenosyl-L-methionine + DNA = S-Adenosyl-L-homocysteine +
            DNA containing 5-methylcytosine
SUBSTRATE   S-Adenosyl-L-methionine
            DNA
PRODUCT     S-Adenosyl-L-homocysteine
            DNA containing 5-methylcytosine
PATHWAY     PATH: MAP00271  Methionine metabolism
DISEASE     MIM: 126375  DNA methyltransferase
MOTIF       PS: PS00094  [DENK]-x-[FLIV]-x(2)-[GSTC]-x-P-C-x(2)-[FYWLIM]-S
            PS: PS00095  [RKQGTF]-x(2)-G-N-[STAG]-[LIVMF]-x(3)-[LIVMT]-x(3)-
                         [LIVM]-x(3)-[LIVM]
GENES       HSA: DNMT(Hs.77462)
STRUCTURES  PDB: 1DCT  1HMY  
DBLINKS     University of Geneva ENZYME DATA BANK: 2.1.1.37
            WIT (What Is There) Metabolic Reconstruction: 2.1.1.37
            SCOP (Structural Classificaion of Proteins): 2.1.1.37
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