ENTRY EC 2.1.1.16
NAME Methylene-fatty-acyl-phospholipid synthase
Unsaturated-phospholipid methyltransferase
CLASS Transferases
Transferring one-carbon groups
Methyltransferases
SYSNAME S-Adenosyl-L-methionine:unsaturated-phospholipid methyltransferase
(methenylating)
REACTION S-Adenosyl-L-methionine + Phospholipid olefinic fatty acid =
S-Adenosyl-L-homocysteine + Phospholipid methylene fatty acid
SUBSTRATE S-Adenosyl-L-methionine
Phospholipid olefinic fatty acid
PRODUCT S-Adenosyl-L-homocysteine
Phospholipid methylene fatty acid
COMMENT The enzyme transfers a methyl group to the 10-position
of a delta-olefinic acyl chain in phosphatidylglycerol or
phosphatidylinositol or, more slowly, phosphatidylethanolamine;
subsequent proton transfer produces a 10-methylene group (cf.
EC 2.1.1.79).
GENES SCE: YJR073C(PEM2)
DBLINKS University of Geneva ENZYME DATA BANK: 2.1.1.16
WIT (What Is There) Metabolic Reconstruction: 2.1.1.16
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